Pradeep Kachroo

Professional Profile




The overall goal of our research is to help understand how specific signaling pathways are induced during host-pathogen interaction, how these pathways communicate with each other and the molecular, genetic and biochemical mechanisms underlying such regulations. We are using Arabidopsis as a model plant system and are studying its interaction with bacterial pathogen Pseudomonas syringae, viral pathogen turnip crinkle virus (TCV) and fungal pathogens Colletotrichum higginsianum and Botrytis cinerea. With regards to signaling mechanisms our main interest is to decipher the role of fatty acid, lipid and cuticular pathways in local and systemic acquired resistance, to characterize resistance (R) protein-mediated signaling and to understand interaction between light and defense signaling.



  • PPA 500: Physiology of Plant Health and Disease
  • PPA 673: Advanced Plant Disease Resistance

Additional Information


Ph.D. in Microbiology, 1995, Maharaja Sayajirao University of Baroda, India & University of Wisconsin-Madison
M.S. in Biotechnology, 1989, Maharaja Sayajirao University of Baroda, India
B.S. (Honors) in Botany, 1987, University of Delhi, India

Employment Highlights

  • Professor, University of Kentucky, 2013-present
  • Associate Professor, University of Kentucky, 2007-2013
  • Assistant Professor, University of Kentucky, 2002-2007
  • Senior Research Associate, Boyce-Thompson Institute, Cornell University, 2000-2003

Awards, Recognition, Service

2009 to Present

  • Prestigious Research Paper Award, Celebration of Land-Grant Research, 2014
  • Current Opinion in Plant Biology, Section Editor, 2013
  • Journal of Integrative Plant Biology, Editor, 2013-present
  • BMC Plant Biology, Deputy Editor, 2009-present
  • Molecular Plant-Microbe Interactions, Associate Editor, 2009-2011
  • Plant Signaling & Behavior, Associate Editor, 2005-present

Professional Affiliations

  • American Society of Plant Biology
  • American Phytopathological Society
  • International Society of Molecular Plant-Microbe Interactions

Selected Research Publications

(2016 to present; see P Kachroo Lab pages for a more complete list)


  • Li D, Liu R, Singh D, Yuan X, Kachroo P, Raina R. (2020) JMJ14 encoded H3K4 demethylase modulates immune responses by regulating defence gene expression and pipecolic acid levels. New Phytologist 225:2108-2121.
  • Kachroo P, Liu H, Kachroo A (2020) Salicylic acid: transport and long-distance immune signaling. Current Opinion in Virology 42:53-57
  • Lim GH, Liu H, Yu K, Liu R, Shine MB, Fernandez J, Burch-Smith T, Mobley JK, McLetchie N, Kachroo A, Kachroo P* (2020) The plant cuticle regulates apoplastic transport of salicylic acid during systemic acquired resistance. Science Advance 6:eaaz0478
  • Kachroo P, Kachroo A (2020) Lipid-modulated trafficking in plants. Molecular Plant 13:351-353


  • Shine MB, Gao QM, Chowda-Reddy RV, Singh AK, Kachroo P, Kachroo A (2019) Glycerol-3- phosphate mediates rhizobia-induced systemic signaling in soybean. Nature Communications 10:5303
  • Lim GH, Zhu S, Zhang K, Hoey T, Deragon JM, Kachroo A, Kachroo P (2019) The analogous and opposing roles of double-stranded RNA-binding proteins in bacterial resistance. Journal of Experimental Botany 70:1627-1638
  • Shine MB, Xiao X, Kachroo P, Kachroo A(2019) Signaling mechanisms underlying systemic acquired resistance to microbial pathogens. Plant Science 279:81-86
  • Kachroo P*, Kachroo A (2019) Plant Immunity: a bird's-eye view. Plant Science 279:1- 2
  • Wang C, Liu R, Lim GH, de Lorenzo L, Yu K, Zhang K, Hunt AG, Kachroo A, Kachroo P (2019) Pipecolic acid confers systemic immunity by regulating free radicals. Science Advance 4:eaar4509


  • Kachroo P, Kachroo A (2018) Plants Pack a Quiver Full of Arrows. Cell Host Microbe. 23:573-575
  • Lim GH, Hoey T, Zhu S, Clavel M, Yu K, Navarre D, Kachroo A, Deragon J-M, Kachroo P (2018) COP1, a negative regulator of photomorphogenesis, positively regulates plant disease resistance via double-stranded RNA binding proteins. PLoS Pathogens 7;14(3):e1006894


  • Kachroo A, Vincelli P, Kachroo P (2017) Systemic signaling in plant defense. Phytopathology 107:1452-1461
  • Lim GH, Singhal R, Kachroo A, Kachroo P (2017)  Fatty acid- and lipid-mediated signaling in plant defense. Annual Review of Phytopathology 55:505-536


  • Shine MB, Yang JW, El-Habbak M, Nagyabhyru P, Fu DQ, Navarre D, Ghabrial S, Kachroo P, Kachroo A (2016) Cooperative functioning between phenylalanine ammonia lyase and isochorishmate synthase activities contributes to salicylic acid biosynthesis in soybean. New Phytologist 212:627-636
  • Lim GH, Kachroo A, Kachroo P. (2016) Role of plasmodesmata and plasmodesmata localizing proteins in systemic immunity. Plant Signaling & Behaviour 11:e1219829
  • Luan H, Shine MB, Cui X, Chen X, Ma N, Kachroo P, Zhi H, Kachroo A. (2016) The potyviral P3 protein targets eEF1A to promote the unfolded protein response and viral pathogenesis. Plant Physiology 172:221-234
  • Lim GH, Shine MB, de Lorenzo L, Yu K, Cui W, Navarre D, Hunt AG, Lee J-Y, Kachroo A, Kachroo P. (2016) Plasmodesmata localizing proteins regulate transport and signaling during systemic immunity. Cell Host & Microbe 19:541-549