Pradeep Kachroo

Professional Profile




The overall goal of our research is to help understand how specific signaling pathways are induced during host-pathogen interaction, how these pathways communicate with each other and the molecular, genetic and biochemical mechanisms underlying such regulations. We are using Arabidopsis as a model plant system and are studying its interaction with bacterial pathogen Pseudomonas syringae, viral pathogen turnip crinkle virus (TCV) and fungal pathogens Colletotrichum higginsianum and Botrytis cinerea. With regards to signaling mechanisms our main interest is to decipher the role of fatty acid, lipid and cuticular pathways in local and systemic acquired resistance, to characterize resistance (R) protein-mediated signaling and to understand interaction between light and defense signaling.



  • PPA 500: Physiology of Plant Health and Disease
  • PPA 673: Advanced Plant Disease Resistance

Additional Information


Ph.D. in Microbiology, 1995, Maharaja Sayajirao University of Baroda, India & University of Wisconsin-Madison
M.S. in Biotechnology, 1989, Maharaja Sayajirao University of Baroda, India
B.S. (Honors) in Botany, 1987, University of Delhi, India

Employment Highlights

  • Professor, University of Kentucky, 2013-present
  • Associate Professor, University of Kentucky, 2007-2013
  • Assistant Professor, University of Kentucky, 2002-2007
  • Senior Research Associate, Boyce-Thompson Institute, Cornell University, 2000-2003

Awards, Recognition, Service

2009 to Present

  • Prestigious Research Paper Award, Celebration of Land-Grant Research, 2014
  • Current Opinion in Plant Biology, Section Editor, 2013
  • Journal of Integrative Plant Biology, Editor, 2013-present
  • BMC Plant Biology, Deputy Editor, 2009-present
  • Molecular Plant-Microbe Interactions, Associate Editor, 2009-2011
  • Plant Signaling & Behavior, Associate Editor, 2005-present

Professional Affiliations

  • American Society of Plant Biology
  • American Phytopathological Society
  • International Society of Molecular Plant-Microbe Interactions

Selected Research Publications

(2012 to present; see P Kachroo Lab pages for a more complete list)


  • Gao QM, Kachroo A, Kachroo P (2014) Chemical inducers of systemic immunity in plants. Journal of Experimental Botany 65: 1849-1855. doi 10.1093/jxb/eru010
  • Gao QM, Yu KS, Xia Y, Shine MB, Wang CX, Navarre D, Kachroo A, Kachroo P (2014) Mono- and digalactosyldiacylglycerol lipids function nonredundantly to regulate systemic acquired resistance in plants. Cell Reports 9: 1681-1691. doi 10.1016/j.celrep.2014.10.069
  • Wang CX, El-Shetehy M, Shine MB, Yu KS, Navarre D, Wendehenne D, Kachroo A, Kachroo P (2014) Free radicals mediate systemic acquired resistance. Cell Reports 7: 348-355. doi 10.1016/j.celrep.2014.03.032
  • Wendehenne D, Gao QM, Kachroo A, Kachroo P (2014) Free radical-mediated systemic immunity in plants. Current Opinion in Plant Biology 20: 127-134. doi 10.1016/j.pbi.2014.05.012
  • Zhu S, Lim G-H, Yu K, Jeong R-D, Kachroo A, Kachroo P (2014) RNA silencing components mediate resistance signaling against turnip crinkle virus. Plant Signaling & Behavior 9: e28435. doi 10.4161/psb.28435


  • Lucas WJ, Groover A, Lichtenberger R, Furuta K, Yadav SR, Helariutta Y, He XQ, Fukuda H, Kang J, Brady SM, Patrick JW, Sperry J, Yoshida A, Lopez-Millan AF, Grusak MA, Kachroo P (2013) The plant vascular system: evolution, development and functions. Journal of Integrative Plant Biology 55: 294-388. doi 10.1111/jipb.12041
  • Glover, B., Kachroo, P. (2013) Variety is the spice of life: the enormous diversity of plant biotic interactions.Current Opinion in Plant Biology 16: 397-399.
  • Yu, K., Soares, J., Mandal, M.K., Wang, C., Chanda, B., Gifford, A.N., Fowler, J.S., Navarre, D., Kachroo, A., Kachroo, P. (2013) A feed-back regulatory loop between glycerol-3-phosphate and lipid transfer proteins DIR1 and AZI1 mediates azelaic acid-induced systemic immunity. Cell Reports 3: 1266-1278.
  • Zhu, S., Jeong, R.-D., Lim, G.-H., Yu, K., Wang, C., Chandra-Shekara, A.C., Navarre, D., Kachroo, A., Kachroo, P. (2013) Double-stranded RNA-binding protein 4 is required for resistance signaling against viral and bacterial pathogens. Cell Reports 4: 1168-1184.


  • Mandal, M.K., Chandra-Shekara, A.C., Jeong, R.-D., Yu, K., Zhu, S., Chanda, B., Navarre, D., Kachroo, A., Kachroo, P. (2012) Oleic acid-dependent modulation of nitric oxide associated 1 protein levels regulates nitric oxide-mediated defense signaling in Arabidopsis. Plant Cell 24, 1654-1674.